hrp0084p2-282 | Diabetes | ESPE2015

Total-Body Irradiation is a Major Risk Factor for Young Adult Onset Diabetes Mellitus and Hyperlipidemia in Childhood Cancer Survivors after Hematopoietic Stem Cell Transplantation

Nakagawa Ryuichi , Tsuji Atsumi , Aoki Yuki , Nakajima Keisuke , Sutani Akito , Miyakawa Yuichi , Takasawa Kei , Tomizawa Daisuke , Takagi Masatoshi , Kashimada Kenichi , Morio Tomohiro

Background: Haematopoietic stem cell transplantation (HSCT) is a risk factor for young adult onset diabetes mellitus (DM) and hyperlipidaemia (HL) as late effects, especially the use of total-body irradiation (TBI). In order to investigate the clinical details, we retrospectively analysed the post-HSCT patients in our institution that required treatment for DM and/or HL.Results: From 1983 to 2012, 24 children received HSCT in our hospital because of haem...